Rafika Brakni, Monia Ali Ahmed, Pauline Burger, Aurélie Schwing, Grégory Michel, Christelle Pomares, Lillia Hasseine, Laurent Boyer, Xavier Fernandez, Anne Landreau, Thomas Michel. (2018), UHPLC-HRMS/MS Based Profiling of Algerian Lichens and Their Antimicrobial Activities. Chemistry and Biodiversityhttps://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.201800031

Résumé: Lichens are complex symbiotic organisms able to produce a vast array of compounds. The Algerian lichen diversity has only prompted little interest even given the 1085 species listed. Herein, the chemodiversity of four Algerian lichens including Cladonia rangiformis, Ramalina farinaceae, R. fastigiata, and Roccella phycopsis was investigated. A dereplication strategy, using ultra high performance liquid chromatography-high resolution-electrospray ionization-mass spectrometry (UHPLC-HRMS/MS), was carried out for a comprehensive characterization of their substances including phenolics, depsides, depsidones, depsones, dibenzofurans, and aliphatic acids. Some known compounds were identified for the first time in some species. Additionally, the lichenic extracts were evaluated for their antifungal and antimicrobial activities on human pathogenic strains (Candida albicans, C. glabrata, Aspergillus fumigatus, Staphylococcus aureus, and Escherichia coli). Cyclohexane extracts were found particularly active against human pathogenic fungi with MIC80 values ranging from 8 to 62.5 μg/mL, without cytotoxicity. This study highlights the therapeutic and prophylactic potential of lichenic extracts as antibacterial and antifungal agents.

ALI AHMED Monia, BRAKNI Rafika, HAMEL Tarek. (2018), Lichen diversity in the Edough Peninsula, North East of Algeria.. Botanica Complutensishttps://dx.doi.org/10.5209/BOCM.61381

Résumé: . This study was carried out with the aim of enriching the list of lichens of Algeria, for this reason we have prospected 2 stations “Les Cascades des Vautours” and “Dar smayer” at 442 and 856 m of altitude, Edough Peninsula on the North East Algerian coast. The annual precipitation is relatively abundant, of the order of 1000 mm. Seventythree taxa were registered belonging to 15 families of which 8 taxa: Cladonia cervicornis subsp. verticillata (Hoffm.) Ahti, C. ramulosa (With.) J.R. Laundon, C. humilis (With.) J.R. Laundon, Nephroma parile (Ach.) Ach., Parmelinopsis afrorevoluta (Krog & Swinscow) Elix & Hale, Ramalina siliquosa (Huds.) A.L. Sm., Usnea esperantiana P. Clerc and Xanthoparmelia conspersa (Ehrh. ex Ach.) Hale, which were never mentioned in Algerian lichen flora.